SS-31

SS-31 (Elamipretide)

SS-31 is a mitochondria-targeting peptide designed to support cellular energy production, mitochondrial integrity, and oxidative stress protection. Unlike traditional metabolic peptides, SS-31 works at the mitochondrial level, directly interacting with cardiolipin to optimize mitochondrial function.

This targeted mechanism helps improve ATP production, enhance cellular resilience, and reduce mitochondrial dysfunction, making SS-31 a powerful research peptide for energy metabolism, cellular repair, and longevity research.

By stabilizing mitochondrial membranes and reducing reactive oxygen species (ROS), SS-31 supports cellular efficiency, tissue recovery, and long-term metabolic health. Research highlights potential benefits in muscle function, cardiovascular performance, neurological health, and age-related cellular decline.

Form & Stability

All Peptide Labs peptides are produced with 99%+ purity and are lyophilized to preserve potency and stability.

• Unmixed (Freeze-Dried):
  Stable for up to 1 year in the refrigerator (2–8°C / 36–46°F) and over 5 years in the freezer (-20°C / -4°F).

• After Reconstitution:
  Store in the refrigerator (2–8°C / 36–46°F) and use within 30 days for optimal results.

Research Overview

1. Mitochondrial Targeting & Energy Production

SS-31 selectively targets mitochondria, binding to cardiolipin to stabilize the inner mitochondrial membrane. This improves electron transport efficiency and enhances ATP synthesis, supporting overall cellular energy output.

2. Oxidative Stress Reduction

Research indicates SS-31 helps reduce mitochondrial oxidative stress by limiting excessive reactive oxygen species (ROS), protecting cells from oxidative damage and supporting cellular longevity.

3. Muscle & Physical Performance Support

By improving mitochondrial efficiency, SS-31 may support muscle endurance, strength preservation, and recovery, particularly in conditions associated with mitochondrial fatigue or aging.

4. Cardiovascular & Metabolic Support

Studies suggest SS-31 may contribute to improved cardiac mitochondrial function, enhanced metabolic efficiency, and better tissue oxygen utilization, supporting overall cardiovascular and metabolic health.

5. Cellular Repair & Longevity Research

SS-31 is widely studied in aging and cellular repair research, with findings indicating potential benefits in maintaining cellular integrity, mitochondrial health, and long-term tissue function.

Molecular Structure

• Sequence: D-Arg-Dmt-Lys-Phe-NH₂

• Molecular Formula: C₃₂H₄₉N₉O₅

• Molecular Weight: 639.8 g/mol

• Form: Lyophilized (freeze-dried) powder for maximum stability