IGF-1LR3

IGF-1 LR3 (Insulin-Like Growth Factor 1 Long R3)

IGF-1 LR3 is a highly bioactive peptide derived from human Insulin-Like Growth Factor-1 (IGF-1), engineered for enhanced stability and extended half-life.

It plays a vital role in cell growth, muscle development, and tissue regeneration by stimulating protein synthesis and promoting the formation of new muscle fibers.

This peptide is recognized for its ability to enhance recovery, improve lean-muscle mass, and accelerate healing — making it a cornerstone compound in research involving muscle hypertrophy, performance, and anti-aging mechanisms.

Form & Stability

All Peptide Labs peptides are produced with 99%+ purity and lyophilized to preserve potency and stability.

• Unmixed (Freeze-Dried): Stable for up to 1 year in the refrigerator (2–8 °C / 36–46 °F) and over 5 years in the freezer (−20 °C / −4 °F).

• After Reconstitution: Store refrigerated (2–8 °C / 36–46 °F) and use within 30 days for optimal results.

Research Overview

1. Muscle Growth & Protein Synthesis

IGF-1 LR3 stimulates muscle cell proliferation and protein synthesis, encouraging the growth of new muscle fibers and the repair of existing ones.

This leads to increased lean-muscle density, enhanced strength, and faster recovery after training or physical stress.

2. Cellular Repair & Recovery

By activating the PI3K/Akt signaling pathway, IGF-1 LR3 promotes cell survival, tissue regeneration, and wound healing.
It supports the recovery of muscle, ligament, and connective tissue, improving repair efficiency after injury or intense exertion.

3. Enhanced Endurance & Performance

Through improved nutrient delivery and mitochondrial efficiency, IGF-1 LR3 increases cellular energy output, resulting in better stamina, performance, and overall vitality.

4. Fat Metabolism & Body Composition

IGF-1 LR3 assists in reducing body fat while maintaining muscle mass, improving overall body composition by shifting metabolism toward lean-tissue growth and fat-utilization.

5. Anti-Aging & Cognitive Support

Research suggests IGF-1 LR3 supports neural growth, cognitive clarity, and tissue longevity, making it beneficial for overall cellular rejuvenation and age-defying performance.

6. Synergy with GH Secretagogues

When combined with peptides such as CJC-1295, Ipamorelin, or Tesamorelin, IGF-1 LR3 can enhance growth-hormone-related pathways, maximizing recovery, muscle gain, and cellular regeneration.

Molecular Structure

• Sequence: Gly-Pro-Glu-Thr-Leu-Cys-Gly-Ala-Glu-Leu-Val-Asp-Ala-Leu-Gln-Phe-Val-Cys-Gly-Asp-Arg-Gly-Phe-Tyr-Phe-Asn-Lys-Pro-Thr-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gly-Lys-Gln-Gly-Val-Ala-Leu-Lys-Pro-Ala-Leu-Ala-Thr-Tyr-Leu-Val-Ala-Leu-Leu-Leu-Pro-Gly-Ala-Glu-Asp-Gly-Tyr-Gly-Phe-Tyr-Thr-Pro-Thr-Lys-Thr-Arg-Gln-Tyr-Arg-Gly-Phe-Ser-Ser-Ser-Ser-Gly-Pro-Glu-Thr-Leu

• Molecular Formula: C₂₆₇H₄₁₁N₆₇O₇₈S

• Molecular Weight: 9111.00 g/mol

• Form: Lyophilized (freeze-dried) powder for maximum stability